Anti-tumor activity of the beta-adrenergic receptor antagonist propranolol in neuroblastoma

Neuroblastoma (NB) is a pediatric tumor of the sympathetic nervous system, which is often associated with elevated catecholamines. More than half of patients with metastatic NB relapse and survival is extremely poor with current therapies. In a high-throughput screen of FDA-approved drugs we identif...

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Bibliographic Details
Main Authors: Wolter, Jennifer K, Wolter, Nikolaus E, Blanch, Alvaro, Partridge, Teresa, Cheng, Lynn, Morgenstern, Daniel A., Podkowa, Monika, Kaplan, David R., Irwin, Meredith S.
Format: Online
Language:English
Published: Impact Journals LLC 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960198/