Targeting nucleocytoplasmic transport in cancer therapy

The intracellular location and regulation of proteins within each cell is critically important and is typically deregulated in disease especially cancer. The clinical hypothesis for inhibiting the nucleo-cytoplasmic transport is based on the dependence of certain key proteins within malignant cells....

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Bibliographic Details
Main Authors: Hill, Richard, Cautain, Bastien, de Pedro, Nuria, Link, Wolfgang
Format: Online
Language:English
Published: Impact Journals LLC 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960186/