Investigation of extraesophageal gastroesophageal reflux disease

The most common extraesophageal manifestations of gastroesophageal reflux disease (GERD) include chronic cough, asthma and laryngitis. There are two mechanisms proposed to explain extraesophageal syndromes caused by GERD. The first one is a direct way via irritation and/or microaspiration and the se...

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Main Authors: Tsoukali, Emmanouela, Sifrim, Daniel
Format: Online
Language:English
Published: Hellenic Society of Gastroenterology 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959476/
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recordtype oai_dc
spelling pubmed-39594762014-04-07 Investigation of extraesophageal gastroesophageal reflux disease Tsoukali, Emmanouela Sifrim, Daniel Invited Review The most common extraesophageal manifestations of gastroesophageal reflux disease (GERD) include chronic cough, asthma and laryngitis. There are two mechanisms proposed to explain extraesophageal syndromes caused by GERD. The first one is a direct way via irritation and/or microaspiration and the second one is an indirect, vagally mediated way. The investigation of extraesophageal manifestations of GERD is difficult and the empirical therapy with proton pump inhibitors usually double dose for at least three months is still the most common approach. Hellenic Society of Gastroenterology 2013 /pmc/articles/PMC3959476/ /pubmed/24714277 Text en Copyright: © Hellenic Society of Gastroenterology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Tsoukali, Emmanouela
Sifrim, Daniel
spellingShingle Tsoukali, Emmanouela
Sifrim, Daniel
Investigation of extraesophageal gastroesophageal reflux disease
author_facet Tsoukali, Emmanouela
Sifrim, Daniel
author_sort Tsoukali, Emmanouela
title Investigation of extraesophageal gastroesophageal reflux disease
title_short Investigation of extraesophageal gastroesophageal reflux disease
title_full Investigation of extraesophageal gastroesophageal reflux disease
title_fullStr Investigation of extraesophageal gastroesophageal reflux disease
title_full_unstemmed Investigation of extraesophageal gastroesophageal reflux disease
title_sort investigation of extraesophageal gastroesophageal reflux disease
description The most common extraesophageal manifestations of gastroesophageal reflux disease (GERD) include chronic cough, asthma and laryngitis. There are two mechanisms proposed to explain extraesophageal syndromes caused by GERD. The first one is a direct way via irritation and/or microaspiration and the second one is an indirect, vagally mediated way. The investigation of extraesophageal manifestations of GERD is difficult and the empirical therapy with proton pump inhibitors usually double dose for at least three months is still the most common approach.
publisher Hellenic Society of Gastroenterology
publishDate 2013
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959476/
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