Clavulanic acid production by the MMS 150 mutant obtained from wild type Streptomyces clavuligerus ATCC 27064

Clavulanic acid (CA) is a powerful inhibitor of the beta-lactamases, enzymes produced by bacteria resistants to penicillin and cefalosporin. This molecule is produced industrially by strains of Streptomyces clavuligerus in complex media which carbon and nitrogen resources are supplied by inexpensive...

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Bibliographic Details
Main Authors: da Silva Vasconcelos, Eliton, de Lima, Vanderlei Aparecido, Goto, Leandro Seiji, Cruz-Hernández, Isara Lourdes, Hokka, Carlos Osamu
Format: Online
Language:English
Published: Brazilian Society of Microbiology 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958168/