ZIP4, a Novel Determinant of Tumor Invasion in Hepatocellular Carcinoma, Contributes to Tumor Recurrence after Liver Transplantation

Background and purpose: Recently, evidence that Zinc transporter ZRT/IRT-like protein 4 (ZIP4) is involved in invasiveness and apoptosis has emerged in pancreatic cancer and prostate cancer. Our aim was to assess the role of ZIP4 in invasiveness, migration and apoptosis of hepatocellular carcinoma (...

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Bibliographic Details
Main Authors: Xu, Xiao, Guo, Hai-Jun, Xie, Hai-Yang, Li, Jie, Zhuang, Run-Zhou, Ling, Qi, Zhou, Lin, Wei, Xu-Yong, Liu, Zhi-Kun, Ding, Song-Ming, Chen, Kang-Jie, Xu, Zhi-Yuan, Zheng, Shu-Sen
Format: Online
Language:English
Published: Ivyspring International Publisher 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957080/
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Summary:Background and purpose: Recently, evidence that Zinc transporter ZRT/IRT-like protein 4 (ZIP4) is involved in invasiveness and apoptosis has emerged in pancreatic cancer and prostate cancer. Our aim was to assess the role of ZIP4 in invasiveness, migration and apoptosis of hepatocellular carcinoma (HCC). The prognostic value of ZIP4 in HCC after liver transplantation was evaluated.