Regulation of mitosis and taxane response by Daxx and Rassf1

Current theories suggest that mitotic checkpoint proteins are essential for proper cellular response to taxanes, a widely-used family of chemotherapeutic compounds. We recently demonstrated that absence or depletion of protein Daxx increases cellular taxol (paclitaxel) resistance—a common trait of p...

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Bibliographic Details
Main Authors: Giovinazzi, Serena, Lindsay, Cory R., Morozov, Viacheslav M., Escobar-Cabrera, Eric, Summers, Matthew K., Han, Hyo Sook, McIntosh, Lawrence P., Ishov, Alexander M.
Format: Online
Language:English
Published: 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954566/