Origin and evolution of the Peptidyl Transferase Center from proto-tRNAs
•We tested the proposal that the Peptidyl Transferase Center (PTC) originated from proto-tRNAs.•Proto-tRNA ancestors were reconstructed.•Their sequences were compared to the sequences of the PTC from several organisms.•We conclude that fusions of proto-tRNAs may have given rise to the PTC.
| Main Authors: | , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
Elsevier
2014
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953717/ |