Rosamines Targeting the Cancer Oxidative Phosphorylation Pathway

Reprogramming of energy metabolism is pivotal to cancer, so mitochondria are potential targets for anticancer therapy. A prior study has demonstrated the anti-proliferative activity of a new class of mitochondria-targeting rosamines. This present study describes in vitro cytotoxicity of second-gener...

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Bibliographic Details
Main Authors: Lim, Siang Hui, Wu, Liangxing, Kiew, Lik Voon, Chung, Lip Yong, Burgess, Kevin, Lee, Hong Boon
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951181/