Co-targeting of convergent nucleotide biosynthetic pathways for leukemia eradication

Co-targeting of both de novo and salvage pathways for dCTP biosynthesis shows efficacy in T-ALL and B-ALL.

Bibliographic Details
Main Authors: Nathanson, David A., Armijo, Amanda L., Tom, Michelle, Li, Zheng, Dimitrova, Elizabeth, Austin, Wayne R., Nomme, Julian, Campbell, Dean O., Ta, Lisa, Le, Thuc M., Lee, Jason T., Darvish, Ryan, Gordin, Ari, Wei, Liu, Liao, Hsiang-I, Wilks, Moses, Martin, Colette, Sadeghi, Saman, Murphy, Jennifer M., Boulos, Nidal, Phelps, Michael E., Faull, Kym F., Herschman, Harvey R., Jung, Michael E., Czernin, Johannes, Lavie, Arnon, Radu, Caius G.
Format: Online
Language:English
Published: The Rockefeller University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949575/
id pubmed-3949575
recordtype oai_dc
spelling pubmed-39495752014-09-10 Co-targeting of convergent nucleotide biosynthetic pathways for leukemia eradication Nathanson, David A. Armijo, Amanda L. Tom, Michelle Li, Zheng Dimitrova, Elizabeth Austin, Wayne R. Nomme, Julian Campbell, Dean O. Ta, Lisa Le, Thuc M. Lee, Jason T. Darvish, Ryan Gordin, Ari Wei, Liu Liao, Hsiang-I Wilks, Moses Martin, Colette Sadeghi, Saman Murphy, Jennifer M. Boulos, Nidal Phelps, Michael E. Faull, Kym F. Herschman, Harvey R. Jung, Michael E. Czernin, Johannes Lavie, Arnon Radu, Caius G. Article Co-targeting of both de novo and salvage pathways for dCTP biosynthesis shows efficacy in T-ALL and B-ALL. The Rockefeller University Press 2014-03-10 /pmc/articles/PMC3949575/ /pubmed/24567448 http://dx.doi.org/10.1084/jem.20131738 Text en © 2014 Nathanson et al. This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Nathanson, David A.
Armijo, Amanda L.
Tom, Michelle
Li, Zheng
Dimitrova, Elizabeth
Austin, Wayne R.
Nomme, Julian
Campbell, Dean O.
Ta, Lisa
Le, Thuc M.
Lee, Jason T.
Darvish, Ryan
Gordin, Ari
Wei, Liu
Liao, Hsiang-I
Wilks, Moses
Martin, Colette
Sadeghi, Saman
Murphy, Jennifer M.
Boulos, Nidal
Phelps, Michael E.
Faull, Kym F.
Herschman, Harvey R.
Jung, Michael E.
Czernin, Johannes
Lavie, Arnon
Radu, Caius G.
spellingShingle Nathanson, David A.
Armijo, Amanda L.
Tom, Michelle
Li, Zheng
Dimitrova, Elizabeth
Austin, Wayne R.
Nomme, Julian
Campbell, Dean O.
Ta, Lisa
Le, Thuc M.
Lee, Jason T.
Darvish, Ryan
Gordin, Ari
Wei, Liu
Liao, Hsiang-I
Wilks, Moses
Martin, Colette
Sadeghi, Saman
Murphy, Jennifer M.
Boulos, Nidal
Phelps, Michael E.
Faull, Kym F.
Herschman, Harvey R.
Jung, Michael E.
Czernin, Johannes
Lavie, Arnon
Radu, Caius G.
Co-targeting of convergent nucleotide biosynthetic pathways for leukemia eradication
author_facet Nathanson, David A.
Armijo, Amanda L.
Tom, Michelle
Li, Zheng
Dimitrova, Elizabeth
Austin, Wayne R.
Nomme, Julian
Campbell, Dean O.
Ta, Lisa
Le, Thuc M.
Lee, Jason T.
Darvish, Ryan
Gordin, Ari
Wei, Liu
Liao, Hsiang-I
Wilks, Moses
Martin, Colette
Sadeghi, Saman
Murphy, Jennifer M.
Boulos, Nidal
Phelps, Michael E.
Faull, Kym F.
Herschman, Harvey R.
Jung, Michael E.
Czernin, Johannes
Lavie, Arnon
Radu, Caius G.
author_sort Nathanson, David A.
title Co-targeting of convergent nucleotide biosynthetic pathways for leukemia eradication
title_short Co-targeting of convergent nucleotide biosynthetic pathways for leukemia eradication
title_full Co-targeting of convergent nucleotide biosynthetic pathways for leukemia eradication
title_fullStr Co-targeting of convergent nucleotide biosynthetic pathways for leukemia eradication
title_full_unstemmed Co-targeting of convergent nucleotide biosynthetic pathways for leukemia eradication
title_sort co-targeting of convergent nucleotide biosynthetic pathways for leukemia eradication
description Co-targeting of both de novo and salvage pathways for dCTP biosynthesis shows efficacy in T-ALL and B-ALL.
publisher The Rockefeller University Press
publishDate 2014
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949575/
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