AMPK: Regulating Energy Balance at the Cellular and Whole Body Levels

AMP-activated protein kinase appears to have evolved in single-celled eukaryotes as an adenine nucleotide sensor that maintains energy homeostasis at the cellular level. However, during evolution of more complex multicellular organisms, the system has adapted to interact with hormones so that it als...

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Bibliographic Details
Main Authors: Hardie, D. Grahame, Ashford, Michael L. J.
Format: Online
Language:English
Published: American Physiological Society 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949207/