MHC-dependent inhibition of uterine NK cells impedes fetal growth and decidual vascular remodelling

NK cells express variable receptors that engage polymorphic MHC class I molecules and regulate their function. Maternal NK cells accumulate at the maternal-fetal interface and can interact with MHC class I molecules from both parents. The relative contribution of the two sets of parental MHC molecul...

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Bibliographic Details
Main Authors: Kieckbusch, Jens, Gaynor, Louise M., Moffett, Ashley, Colucci, Francesco
Format: Online
Language:English
Published: Nature Publishing Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948146/