An Essential Role for Medullary Thymic Epithelial Cells during the Intrathymic Development of Invariant NKT Cells

An Essential Role for Medullary Thymic Epithelial Cells during the Intrathymic Development of Invariant NKT Cells

In the thymus, interactions with both cortical and medullary microenvironments regulate the development of self-tolerant conventional CD4+ and CD8+ αβT cells expressing a wide range of αβTCR specificities. Additionally, the cortex is also required for the development of invariant NKT (iNKT) cells, a...

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Bibliographic Details
Main Authors: White, Andrea J., Jenkinson, William E., Cowan, Jennifer E., Parnell, Sonia M., Bacon, Andrea, Jones, Nick D., Jenkinson, Eric J., Anderson, Graham
Format: Online
Language:English
Published: AAI 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948113/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948113/

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