Targeted Peptide Measurements in Biology and Medicine: Best Practices for Mass Spectrometry-based Assay Development Using a Fit-for-Purpose Approach*

Adoption of targeted mass spectrometry (MS) approaches such as multiple reaction monitoring (MRM) to study biological and biomedical questions is well underway in the proteomics community. Successful application depends on the ability to generate reliable assays that uniquely and confidently identif...

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Bibliographic Details
Main Authors: Carr, Steven A., Abbatiello, Susan E., Ackermann, Bradley L., Borchers, Christoph, Domon, Bruno, Deutsch, Eric W., Grant, Russell P., Hoofnagle, Andrew N., Hüttenhain, Ruth, Koomen, John M., Liebler, Daniel C., Liu, Tao, MacLean, Brendan, Mani, DR, Mansfield, Elizabeth, Neubert, Hendrik, Paulovich, Amanda G., Reiter, Lukas, Vitek, Olga, Aebersold, Ruedi, Anderson, Leigh, Bethem, Robert, Blonder, Josip, Boja, Emily, Botelho, Julianne, Boyne, Michael, Bradshaw, Ralph A., Burlingame, Alma L., Chan, Daniel, Keshishian, Hasmik, Kuhn, Eric, Kinsinger, Christopher, Lee, Jerry S.H., Lee, Sang-Won, Moritz, Robert, Oses-Prieto, Juan, Rifai, Nader, Ritchie, James, Rodriguez, Henry, Srinivas, Pothur R., Townsend, R. Reid, Van Eyk, Jennifer, Whiteley, Gordon, Wiita, Arun, Weintraub, Susan
Format: Online
Language:English
Published: The American Society for Biochemistry and Molecular Biology 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945918/