Epigallocatechin-3-gallate Ameliorates Seawater Aspiration-Induced Acute Lung Injury via Regulating Inflammatory Cytokines and Inhibiting JAK/STAT1 Pathway in Rats

Signal transducers and activators of transcriptions 1 (STAT1) play an important role in the inflammation process of acute lung injury (ALI). Epigallocatechin-3-gallate (EGCG) exhibits a specific and strong anti-STAT1 activity. Therefore, our study is to explore whether EGCG pretreatment can ameliora...

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Bibliographic Details
Main Authors: Liu, Wei, Dong, Mingqing, Bo, Liyan, Li, Congcong, Liu, Qingqing, Li, Yanyan, Ma, Lijie, Xie, Yonghong, Fu, Enqing, Mu, Deguang, Pan, Lei, Jin, Faguang, Li, Zhichao
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945896/