ALS-linked SOD1 in glial cells enhances ß-N-Methylamino L-Alanine (BMAA)-induced toxicity in Drosophila

Environmental factors have been implicated in the etiology of a number of neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS). However, the role of environmental agents in ALS remains poorly understood. To this end, we used transgenic fruit flies (Drosophila melanogaster) to ex...

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Bibliographic Details
Main Authors: Islam, Rafique, Kumimoto, Emily L, Bao, Hong, Zhang, Bing
Format: Online
Language:English
Published: F1000Research 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945777/