Differential Stability of the Crystallographic Interfaces of Mu- and Kappa-Opioid Receptors

The recent mu-opioid receptor (MOPr) and kappa-opioid receptor (KOPr) crystal structures have inspired hypotheses of physiologically relevant dimerization contacts, specifically: a closely packed interface involving transmembrane (TM) helices TM5 and TM6, and a less compact interface, involving TM1,...

Full description

Bibliographic Details
Main Authors: Johnston, Jennifer M., Filizola, Marta
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944890/