Neisseria meningitidis Serogroup W, Burkina Faso, 2012

Neisseria meningitidis Serogroup W, Burkina Faso, 2012

In 2010, Burkina Faso became the first country to introduce meningococcal serogroup A conjugate vaccine (PsA-TT). During 2012, Burkina Faso reported increases in Neisseria meningitidis serogroup W, raising questions about whether these cases were a natural increase in disease or resulted from serogr...

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Main Authors: MacNeil, Jessica R., Medah, Isaïe, Koussoubé, Daouda, Novak, Ryan T., Cohn, Amanda C., Diomandé, Fabien V.K., Yelbeogo, Denis, Kambou, Jean Ludovic, Tarbangdo, Tiga F., Ouédraogo-Traoré, Rasmata, Sangaré, Lassana, Hatcher, Cynthia, Vuong, Jeni, Mayer, Leonard W., Djingarey, Mamoudou H., Clark, Thomas A., Messonnier, Nancy E.
Format: Online
Language:English
Published: Centers for Disease Control and Prevention 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944835/
id pubmed-3944835
recordtype oai_dc
spelling pubmed-39448352014-03-12 Neisseria meningitidis Serogroup W, Burkina Faso, 2012 MacNeil, Jessica R. Medah, Isaïe Koussoubé, Daouda Novak, Ryan T. Cohn, Amanda C. Diomandé, Fabien V.K. Yelbeogo, Denis Kambou, Jean Ludovic Tarbangdo, Tiga F. Ouédraogo-Traoré, Rasmata Sangaré, Lassana Hatcher, Cynthia Vuong, Jeni Mayer, Leonard W. Djingarey, Mamoudou H. Clark, Thomas A. Messonnier, Nancy E. Research In 2010, Burkina Faso became the first country to introduce meningococcal serogroup A conjugate vaccine (PsA-TT). During 2012, Burkina Faso reported increases in Neisseria meningitidis serogroup W, raising questions about whether these cases were a natural increase in disease or resulted from serogroup replacement after PsA-TT introduction. We analyzed national surveillance data to describe the epidemiology of serogroup W and genotyped 61 serogroup W isolates. In 2012, a total of 5,807 meningitis cases were reported through enhanced surveillance, of which 2,353 (41%) were laboratory confirmed. The predominant organism identified was N. meningitidis serogroup W (62%), and all serogroup W isolates characterized belonged to clonal complex 11. Although additional years of data are needed before we can understand the epidemiology of serogroup W after PsA–TT introduction, these data suggest that serogroup W will remain a major cause of sporadic disease and has epidemic potential, underscoring the need to maintain high-quality case-based meningitis surveillance after PsA–TT introduction. Centers for Disease Control and Prevention 2014-03 /pmc/articles/PMC3944835/ /pubmed/24571805 http://dx.doi.org/10.3201/eid2003.131407 Text en
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author MacNeil, Jessica R.
Medah, Isaïe
Koussoubé, Daouda
Novak, Ryan T.
Cohn, Amanda C.
Diomandé, Fabien V.K.
Yelbeogo, Denis
Kambou, Jean Ludovic
Tarbangdo, Tiga F.
Ouédraogo-Traoré, Rasmata
Sangaré, Lassana
Hatcher, Cynthia
Vuong, Jeni
Mayer, Leonard W.
Djingarey, Mamoudou H.
Clark, Thomas A.
Messonnier, Nancy E.
spellingShingle MacNeil, Jessica R.
Medah, Isaïe
Koussoubé, Daouda
Novak, Ryan T.
Cohn, Amanda C.
Diomandé, Fabien V.K.
Yelbeogo, Denis
Kambou, Jean Ludovic
Tarbangdo, Tiga F.
Ouédraogo-Traoré, Rasmata
Sangaré, Lassana
Hatcher, Cynthia
Vuong, Jeni
Mayer, Leonard W.
Djingarey, Mamoudou H.
Clark, Thomas A.
Messonnier, Nancy E.
Neisseria meningitidis Serogroup W, Burkina Faso, 2012
author_facet MacNeil, Jessica R.
Medah, Isaïe
Koussoubé, Daouda
Novak, Ryan T.
Cohn, Amanda C.
Diomandé, Fabien V.K.
Yelbeogo, Denis
Kambou, Jean Ludovic
Tarbangdo, Tiga F.
Ouédraogo-Traoré, Rasmata
Sangaré, Lassana
Hatcher, Cynthia
Vuong, Jeni
Mayer, Leonard W.
Djingarey, Mamoudou H.
Clark, Thomas A.
Messonnier, Nancy E.
author_sort MacNeil, Jessica R.
title Neisseria meningitidis Serogroup W, Burkina Faso, 2012
title_short Neisseria meningitidis Serogroup W, Burkina Faso, 2012
title_full Neisseria meningitidis Serogroup W, Burkina Faso, 2012
title_fullStr Neisseria meningitidis Serogroup W, Burkina Faso, 2012
title_full_unstemmed Neisseria meningitidis Serogroup W, Burkina Faso, 2012
title_sort neisseria meningitidis serogroup w, burkina faso, 2012
description In 2010, Burkina Faso became the first country to introduce meningococcal serogroup A conjugate vaccine (PsA-TT). During 2012, Burkina Faso reported increases in Neisseria meningitidis serogroup W, raising questions about whether these cases were a natural increase in disease or resulted from serogroup replacement after PsA-TT introduction. We analyzed national surveillance data to describe the epidemiology of serogroup W and genotyped 61 serogroup W isolates. In 2012, a total of 5,807 meningitis cases were reported through enhanced surveillance, of which 2,353 (41%) were laboratory confirmed. The predominant organism identified was N. meningitidis serogroup W (62%), and all serogroup W isolates characterized belonged to clonal complex 11. Although additional years of data are needed before we can understand the epidemiology of serogroup W after PsA–TT introduction, these data suggest that serogroup W will remain a major cause of sporadic disease and has epidemic potential, underscoring the need to maintain high-quality case-based meningitis surveillance after PsA–TT introduction.
publisher Centers for Disease Control and Prevention
publishDate 2014
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944835/
_version_ 1612065171137626112

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