Expression of the Murine Norovirus (MNV) ORF1 Polyprotein Is Sufficient to Induce Apoptosis in a Virus-Free Cell Model

Investigations into human norovirus infection, replication and pathogenesis, as well as the development of potential antiviral agents, have been restricted by the lack of a cell culture system for human norovirus. To date, the optimal cell culture surrogate virus model for studying human norovirus b...

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Bibliographic Details
Main Authors: Herod, Morgan R., Salim, Omar, Skilton, Rachel J., Prince, Cynthia A., Ward, Vernon K., Lambden, Paul R., Clarke, Ian N.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944349/