Parkinson's Disease Gene Therapy: Success by Design Meets Failure by Efficacy

Over the past decade, nine gene therapy clinical trials for Parkinson's disease (PD) have been initiated and completed. Starting with considerable optimism at the initiation of each trial, none of the programs has yet borne sufficiently robust clinical efficacy or found a clear path toward regu...

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Bibliographic Details
Main Authors: Bartus, Raymond T, Weinberg, Marc S, Samulski, R. Jude
Format: Online
Language:English
Published: Nature Publishing Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944322/