Epstein-Barr virus and telomerase: from cell immortalization to therapy
Overcoming cellular senescence is strictly required for virus-driven tumors, including those associated with Epstein-Barr virus (EBV). This critical step is successfully accomplished by EBV through TERT expression and telomerase activation in infected cells. We herein review the complex interplay be...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
BioMed Central
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943417/ |