Synchronization Using PGF2α and Estradiol With or Without GnRH for Timed Artificial Insemination in Dairy Cows
This study examined the use of PGF2α and estradiol benzoate (EB) either with or without GnRH to synchronize estrus in dairy cows for timed artificial insemination (TAI) under field conditions. First, Holstein dairy cows with a corpus luteum (CL) received 500 μg cloprostenol and were then randomly a...
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| Format: | Online |
| Language: | English |
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The Society for Reproduction and Development
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943234/ |
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pubmed-39432342014-03-06 Synchronization Using PGF2α and Estradiol With or Without GnRH for Timed Artificial Insemination in Dairy Cows JEONG, Jae Kwan KANG, Hyun Gu HUR, Tai Young KIM, Ill Hwa Technology Report This study examined the use of PGF2α and estradiol benzoate (EB) either with or without GnRH to synchronize estrus in dairy cows for timed artificial insemination (TAI) under field conditions. First, Holstein dairy cows with a corpus luteum (CL) received 500 μg cloprostenol and were then randomly allocated to three groups: no further treatment (control, n=236); treatment with 1 mg EB 56 h after cloprostenol (EB group, n=339); or treatment with 1 mg EB 56 h after cloprostenol followed by treatment with 100 μg gonadorelin 24 h later (EB + GnRH group, n=216). All cows received TAI 80 h after the cloprostenol injection. In a second experiment, Holstein dairy cows with a CL received 500 μg cloprostenol and were then randomly allocated to two groups: treatment with 2 mg EB 36 h later (EB group, n=284) or treatment with 2 mg EB 36 h after cloprostenol followed by 100 μg gonadorelin 24 h later (EB + GnRH group, n=229). All cows received TAI 24 h after the EB injection. Logistic analyses revealed that the odds ratio for the probability of pregnancy when 1 mg EB was administered 56 h following cloprostenol was 1.9 and 2.0 times (P<0.001) higher in the EB (39.5%) and EB + GnRH groups (40.7%), respectively, compared with the control group (25.8%). However, pregnancy rates in cows receiving 2 mg EB 24 h following cloprostenol showed no difference compared with cows treated with EB only (32.4%) or with EB + GnRH (35.8%). These results indicate that a synchronization protocol comprising PGF2α and EB could be used for TAI in dairy herds under field conditions. The Society for Reproduction and Development 2012-10-11 2013-02 /pmc/articles/PMC3943234/ /pubmed/23059639 http://dx.doi.org/10.1262/jrd.2012-117 Text en ©2013 Society for Reproduction and Development http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
JEONG, Jae Kwan KANG, Hyun Gu HUR, Tai Young KIM, Ill Hwa |
| spellingShingle |
JEONG, Jae Kwan KANG, Hyun Gu HUR, Tai Young KIM, Ill Hwa Synchronization Using PGF2α and Estradiol With or Without GnRH for Timed Artificial Insemination in Dairy Cows |
| author_facet |
JEONG, Jae Kwan KANG, Hyun Gu HUR, Tai Young KIM, Ill Hwa |
| author_sort |
JEONG, Jae Kwan |
| title |
Synchronization Using PGF2α and Estradiol With or Without GnRH for
Timed Artificial Insemination in Dairy Cows |
| title_short |
Synchronization Using PGF2α and Estradiol With or Without GnRH for
Timed Artificial Insemination in Dairy Cows |
| title_full |
Synchronization Using PGF2α and Estradiol With or Without GnRH for
Timed Artificial Insemination in Dairy Cows |
| title_fullStr |
Synchronization Using PGF2α and Estradiol With or Without GnRH for
Timed Artificial Insemination in Dairy Cows |
| title_full_unstemmed |
Synchronization Using PGF2α and Estradiol With or Without GnRH for
Timed Artificial Insemination in Dairy Cows |
| title_sort |
synchronization using pgf2α and estradiol with or without gnrh for
timed artificial insemination in dairy cows |
| description |
This study examined the use of PGF2α and estradiol benzoate (EB) either with
or without GnRH to synchronize estrus in dairy cows for timed artificial insemination
(TAI) under field conditions. First, Holstein dairy cows with a corpus luteum (CL)
received 500 μg cloprostenol and were then randomly allocated to three groups: no further
treatment (control, n=236); treatment with 1 mg EB 56 h after cloprostenol (EB group,
n=339); or treatment with 1 mg EB 56 h after cloprostenol followed by treatment with 100
μg gonadorelin 24 h later (EB + GnRH group, n=216). All cows received TAI 80 h after the
cloprostenol injection. In a second experiment, Holstein dairy cows with a CL received 500
μg cloprostenol and were then randomly allocated to two groups: treatment with 2 mg EB 36
h later (EB group, n=284) or treatment with 2 mg EB 36 h after cloprostenol followed by
100 μg gonadorelin 24 h later (EB + GnRH group, n=229). All cows received TAI 24 h after
the EB injection. Logistic analyses revealed that the odds ratio for the probability of
pregnancy when 1 mg EB was administered 56 h following cloprostenol was 1.9 and 2.0 times
(P<0.001) higher in the EB (39.5%) and EB + GnRH groups (40.7%), respectively, compared
with the control group (25.8%). However, pregnancy rates in cows receiving 2 mg EB 24 h
following cloprostenol showed no difference compared with cows treated with EB only
(32.4%) or with EB + GnRH (35.8%). These results indicate that a synchronization protocol
comprising PGF2α and EB could be used for TAI in dairy herds under field
conditions. |
| publisher |
The Society for Reproduction and Development |
| publishDate |
2012 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943234/ |
| _version_ |
1612064664220336128 |