Dermal Cell Damage Induced by Topical Application of Non-Steroidal Anti-Inflammatory Drugs is Suppressed by Trehalose Co-Lyophilization in Ex Vivo Analysis

Topical administration of non-steroidal anti-inflammatory drugs (NSAIDs) is generally considered safer than oral administration, although the former can occasionally induce cutaneous irritation. We hypothesized that the cutaneous irritation by topical NSAIDs might be suppressed by trehalose, which...

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Bibliographic Details
Main Authors: KAYASUGA-KARIYA, Yuko, IWANAGA, Shintaroh, FUJISAWA, Ayano, LIN, Lee-Shuan, SUZUKI, Shigeki, CHUNG, Ung-il, SASAKI, Nobuo, SHIMOHATA, Nobuyuki, MOCHIZUKI, Manabu
Format: Online
Language:English
Published: The Japanese Society of Veterinary Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942957/