Detection of Ascitic Feline Coronavirus RNA from Cats with Clinically Suspected Feline Infectious Peritonitis

Detection of Ascitic Feline Coronavirus RNA from Cats with Clinically Suspected Feline Infectious Peritonitis

Ascitic feline coronavirus (FCoV) RNA was examined in 854 cats with suspected feline infectious peritonitis (FIP) by RT-PCR. The positivity was significantly higher in purebreds (62.2%) than in crossbreds (34.8%) (P<0.0001). Among purebreds, the positivities in the Norwegian forest cat (92.3%) an...

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Main Authors: SOMA, Takehisa, WADA, Makoto, TAHARAGUCHI, Satoshi, TAJIMA, Tomoko
Format: Online
Language:English
Published: The Japanese Society of Veterinary Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942943/
id pubmed-3942943
recordtype oai_dc
spelling pubmed-39429432014-04-22 Detection of Ascitic Feline Coronavirus RNA from Cats with Clinically Suspected Feline Infectious Peritonitis SOMA, Takehisa WADA, Makoto TAHARAGUCHI, Satoshi TAJIMA, Tomoko Virology Ascitic feline coronavirus (FCoV) RNA was examined in 854 cats with suspected feline infectious peritonitis (FIP) by RT-PCR. The positivity was significantly higher in purebreds (62.2%) than in crossbreds (34.8%) (P<0.0001). Among purebreds, the positivities in the Norwegian forest cat (92.3%) and Scottish fold (77.6%) were significantly higher than the average of purebreds (P=0.0274 and 0.0251, respectively). The positivity was significantly higher in males (51.5%) than in females (35.7%) (P<0.0001), whereas no gender difference has generally been noted in FCoV antibody prevalence, indicating that FIP more frequently develops in males among FCoV-infected cats. Genotyping was performed for 377 gene-positive specimens. Type I (83.3%) was far more predominantly detected than type II (10.6%) (P<0.0001), similar to previous serological and genetic surveys. The Japanese Society of Veterinary Science 2013-05-29 2013-10 /pmc/articles/PMC3942943/ /pubmed/23719724 http://dx.doi.org/10.1292/jvms.13-0094 Text en ©2013 The Japanese Society of Veterinary Science http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author SOMA, Takehisa
WADA, Makoto
TAHARAGUCHI, Satoshi
TAJIMA, Tomoko
spellingShingle SOMA, Takehisa
WADA, Makoto
TAHARAGUCHI, Satoshi
TAJIMA, Tomoko
Detection of Ascitic Feline Coronavirus RNA from Cats with Clinically Suspected Feline Infectious Peritonitis
author_facet SOMA, Takehisa
WADA, Makoto
TAHARAGUCHI, Satoshi
TAJIMA, Tomoko
author_sort SOMA, Takehisa
title Detection of Ascitic Feline Coronavirus RNA from Cats with Clinically Suspected Feline Infectious Peritonitis
title_short Detection of Ascitic Feline Coronavirus RNA from Cats with Clinically Suspected Feline Infectious Peritonitis
title_full Detection of Ascitic Feline Coronavirus RNA from Cats with Clinically Suspected Feline Infectious Peritonitis
title_fullStr Detection of Ascitic Feline Coronavirus RNA from Cats with Clinically Suspected Feline Infectious Peritonitis
title_full_unstemmed Detection of Ascitic Feline Coronavirus RNA from Cats with Clinically Suspected Feline Infectious Peritonitis
title_sort detection of ascitic feline coronavirus rna from cats with clinically suspected feline infectious peritonitis
description Ascitic feline coronavirus (FCoV) RNA was examined in 854 cats with suspected feline infectious peritonitis (FIP) by RT-PCR. The positivity was significantly higher in purebreds (62.2%) than in crossbreds (34.8%) (P<0.0001). Among purebreds, the positivities in the Norwegian forest cat (92.3%) and Scottish fold (77.6%) were significantly higher than the average of purebreds (P=0.0274 and 0.0251, respectively). The positivity was significantly higher in males (51.5%) than in females (35.7%) (P<0.0001), whereas no gender difference has generally been noted in FCoV antibody prevalence, indicating that FIP more frequently develops in males among FCoV-infected cats. Genotyping was performed for 377 gene-positive specimens. Type I (83.3%) was far more predominantly detected than type II (10.6%) (P<0.0001), similar to previous serological and genetic surveys.
publisher The Japanese Society of Veterinary Science
publishDate 2013
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942943/
_version_ 1612064522057547776

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