Germline Transmission of an Embryonic Stem Cell Line Derived from BALB/c Cataract Mice

Mice embryonic stem (ES) cells have enabled the generation of mouse strains with defined mutation(s) in their genome for putative disease loci analysis. In the study of cataract, the complex genetic background of this disease and lack of long-term self-renewal ES cells have hampered the functional r...

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Bibliographic Details
Main Authors: Peng, Xinrong, Liu, Tao, Shi, Chuanyin, Zhang, Liqing, Wang, Ying, Zhao, Wuyang, Jiang, Lihua, Wu, Mengchao, Zhang, Yong, Qian, Qijun
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942454/