Lipopolysaccharide Induces Inflammatory Hyperalgesia Triggering a TLR4/MyD88-Dependent Cytokine Cascade in the Mice Paw

Lipopolysaccharide Induces Inflammatory Hyperalgesia Triggering a TLR4/MyD88-Dependent Cytokine Cascade in the Mice Paw

Inflammatory pain can be triggered by different stimuli, such as trauma, radiation, antigen and infection. In a model of inflammatory pain caused by infection, injection in the mice paw of lipopolysaccharide (LPS), a Toll-like receptor 4 (TLR4) agonist, produces mechanical hyperalgesia. We identify...

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Bibliographic Details
Main Authors: Calil, Igor L., Zarpelon, Ana C., Guerrero, Ana T. G., Alves-Filho, Jose C., Ferreira, Sergio H., Cunha, Fernando Q., Cunha, Thiago M., Verri, Waldiceu A.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940714/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940714/

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