Micron-scale Resolution Optical Tomography of Entire Mouse Brains with Confocal Light Sheet Microscopy

Understanding the architecture of mammalian brain at single-cell resolution is one of the key issues of neuroscience. However, mapping neuronal soma and projections throughout the whole brain is still challenging for imaging and data management technologies. Indeed, macroscopic volumes need to be re...

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Bibliographic Details
Main Authors: Silvestri, Ludovico, Bria, Alessandro, Costantini, Irene, Sacconi, Leonardo, Peng, Hanchuan, Iannello, Giulio, Pavone, Francesco Saverio
Format: Online
Language:English
Published: MyJove Corporation 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3939053/