Design of inhibitors of the HIV-1 integrase core domain using virtual screening

Acquired immunodeficiency syndrome (AIDS) is a disease of the human immune system caused by the human immunodeficiency virus (HIV). The integrase (IN) enzyme of HIV interacts with several cellular and viral proteins during the integration process. Thus, it represents an appropriate target for antire...

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Bibliographic Details
Main Authors: Regon, Preetom, Gogoi, Dhrubajyoti, Rai, Ashok Kumar, Bordoloi, Manabjyoti, Bezbaruah, Rajib Lochan
Format: Online
Language:English
Published: Biomedical Informatics 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937579/