Learning Gene Networks under SNP Perturbations Using eQTL Datasets

The standard approach for identifying gene networks is based on experimental perturbations of gene regulatory systems such as gene knock-out experiments, followed by a genome-wide profiling of differential gene expressions. However, this approach is significantly limited in that it is not possible t...

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Bibliographic Details
Main Authors: Zhang, Lingxue, Kim, Seyoung
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937098/