Differences between cotranscriptional and free riboswitch folding

Riboswitches are part of noncoding regions of messenger RNA (mRNA) that act as RNA sensors regulating gene expression of the downstream gene. Typically, one out of two distinct conformations is formed depending on ligand binding when the transcript leaves RNA polymerase (RNAP). Elongation of the RNA...

Full description

Bibliographic Details
Main Authors: Lutz, Benjamin, Faber, Michael, Verma, Abhinav, Klumpp, Stefan, Schug, Alexander
Format: Online
Language:English
Published: Oxford University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936736/