Modification of picornavirus genomic RNA using ‘click’ chemistry shows that unlinking of the VPg peptide is dispensable for translation and replication of the incoming viral RNA

Modification of picornavirus genomic RNA using ‘click’ chemistry shows that unlinking of the VPg peptide is dispensable for translation and replication of the incoming viral RNA

Picornaviruses constitute a large group of viruses comprising medically and economically important pathogens such as poliovirus, coxsackievirus, rhinovirus, enterovirus 71 and foot-and-mouth disease virus. A unique characteristic of these viruses is the use of a viral peptide (VPg) as primer for vir...

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Bibliographic Details
Main Authors: Langereis, Martijn A., Feng, Qian, Nelissen, Frank H. T., Virgen-Slane, Richard, van der Heden van Noort, Gerbrand J., Maciejewski, Sonia, Filippov, Dmitri V., Semler, Bert L., van Delft, Floris L., van Kuppeveld, Frank J.M.
Format: Online
Language:English
Published: Oxford University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936719/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936719/

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