Clonogenicity: Holoclones and Meroclones Contain Stem Cells

When primary cultures of normal cells are cloned, three types of colony grow, called holoclones, meroclones and paraclones. These colonies are believed to be derived from stem cells, transit-amplifying cells and differentiated cells respectively. More recently, this approach has been extended to can...

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Bibliographic Details
Main Authors: Beaver, Charlotte M., Ahmed, Aamir, Masters, John R.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935944/