Physiological implications of NTBI uptake by T lymphocytes
In iron overload disorders a significant fraction of the total iron circulates in the plasma as low molecular weight complexes not bound to transferrin, known as non-transferrin-bound iron (NTBI). By catalyzing the formation of free radicals, NTBI accumulation results in oxidative stress and cellula...
Main Authors: | Pinto, Jorge P., Arezes, João, Dias, Vera, Oliveira, Susana, Vieira, Inês, Costa, Mónica, Vos, Matthijn, Carlsson, Anna, Rikers, Yuri, Rangel, Maria, Porto, Graça |
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Format: | Online |
Language: | English |
Published: |
Frontiers Media S.A.
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935319/ |
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