Magnesium Inhibits Wnt/β-Catenin Activity and Reverses the Osteogenic Transformation of Vascular Smooth Muscle Cells

Magnesium reduces vascular smooth muscle cell (VSMC) calcification in vitro but the mechanism has not been revealed so far. This work used only slightly increased magnesium levels and aimed at determining: a) whether inhibition of magnesium transport into the cell influences VSMC calcification, b) w...

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Bibliographic Details
Main Authors: Montes de Oca, Addy, Guerrero, Fatima, Martinez-Moreno, Julio M., Madueño, Juan A., Herencia, Carmen, Peralta, Alan, Almaden, Yolanda, Lopez, Ignacio, Aguilera-Tejero, Escolastico, Gundlach, Kristina, Büchel, Janine, Peter, Mirjam E., Passlick-Deetjen, Jutta, Rodriguez, Mariano, Muñoz-Castañeda, Juan R.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934896/