Activity-dependent regulation of NMDA receptors in substantia nigra dopaminergic neurones
N-Methyl-d-aspartate receptors (NMDARs) are Ca2+-permeable glutamate receptors that play a critical role in synaptic plasticity and promoting cell survival. However, overactive NMDARs can trigger cell death signalling pathways and have been implicated in substantia nigra pars compacta (SNc) patholog...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
Blackwell Publishing Ltd
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934707/ |