Variability of the Transferrin Receptor 2 Gene in AMD

Oxidative stress is a major factor in the pathogenesis of age-related macular degeneration (AMD). Iron may catalyze the Fenton reaction resulting in overproduction of reactive oxygen species. Transferrin receptor 2 plays a critical role in iron homeostasis and variability in its gene may influence o...

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Bibliographic Details
Main Authors: Wysokinski, Daniel, Blasiak, Janusz, Dorecka, Mariola, Kowalska, Marta, Robaszkiewicz, Jacek, Pawlowska, Elzbieta, Szaflik, Jerzy, Szaflik, Jacek Pawel
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933306/