Angiotensin II-induced delayed stimulation of phospholipase C γ1 requires activation of both phosphatidiylinositol 3-kinase γ and tyrosine kinase in vascular myocytes

In vascular smooth muscles, angiotensin II (AII) has been reported to activate phospholipase C (PLC) and phosphatidylinositol 3-kinase (PI3K). We investigated the time-dependent effects of AII on both phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol phosphates (InsPs) accumulation in...

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Bibliographic Details
Main Authors: Rakotoarisoa, Lala, Carricaburu, Valérie, Leblanc, Catherine, Mironneau, Chantal, Mironneau, Jean, Macrez, Nathalie
Format: Online
Language:English
Published: John Wiley & Sons, Ltd 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933155/