Substance P and Neurokinin 1 receptor - expression is affected in the ileum of mice with mutation in the W locus

The tachykinin substance P (SP) acts on the gut muscle coat via its preferred receptor, neurokinin 1 (NK1r). In the mouse ileum, NK1r-immunoreactivity (NK1r-IR) was detected in neurons, in the interstitial cells of Cajal at the deep muscular plexus (ICC-DMP) and the myoid cells of the villi. SP-IR w...

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Bibliographic Details
Main Authors: Faussone-Pellegrini, Maria-Simonetta, Vannucchi, Maria-Giuliana
Format: Online
Language:English
Published: John Wiley & Sons, Ltd 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933138/