Protein carbonylation, cellular dysfunction, and disease progression
Carbonylation of proteins is an irreversible oxidative damage, often leading to a loss of protein function, which is considered a widespread indicator of severe oxidative damage and disease-derived protein dysfunction. Whereas moderately carbonylated proteins are degraded by the proteasomal system,...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
John Wiley & Sons, Ltd
2006
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933129/ |