Energy Parameters and Novel Algorithms for an Extended Nearest Neighbor Energy Model of RNA

We describe the first algorithm and software, RNAenn, to compute the partition function and minimum free energy secondary structure for RNA with respect to an extended nearest neighbor energy model. Our next-nearest-neighbor triplet energy model appears to lead to somewhat more cooperative folding t...

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Bibliographic Details
Main Authors: Dotu, Ivan, Mechery, Vinodh, Clote, Peter
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931620/