Modulation of Wnt Activity and Cell Physiology by Butyrate in LT97 Microadenoma Cells

Dietary fiber intake is linked to a reduced risk of colon cancer. This effect may in part be due to butyrate, the fermentation product of fiber in the colon. Butyrate is a short-chain fatty acid that acts as a histone deacetylase inhibitor (HDACi). Butyrate induces apoptosis and represses clonal gro...

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Bibliographic Details
Main Authors: Lazarova, Darina, Lee, Andrew, Wong, Terrence, Marian, Brigitte, Chiaro, Christopher, Rainey, Christian, Bordonaro, Michael
Format: Online
Language:English
Published: Ivyspring International Publisher 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931268/