Image-Derived Input Function Derived from a Supervised Clustering Algorithm: Methodology and Validation in a Clinical Protocol Using [11C](R)-Rolipram

Image-derived input function (IDIF) obtained by manually drawing carotid arteries (manual-IDIF) can be reliably used in [11C](R)-rolipram positron emission tomography (PET) scans. However, manual-IDIF is time consuming and subject to inter- and intra-operator variability. To overcome this limitation...

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Main Authors: Lyoo, Chul Hyoung, Zanotti-Fregonara, Paolo, Zoghbi, Sami S., Liow, Jeih-San, Xu, Rong, Pike, Victor W., Zarate, Carlos A., Fujita, Masahiro, Innis, Robert B.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930688/