Quantitative Genome-Wide Genetic Interaction Screens Reveal Global Epistatic Relationships of Protein Complexes in Escherichia coli

Quantitative Genome-Wide Genetic Interaction Screens Reveal Global Epistatic Relationships of Protein Complexes in Escherichia coli

Large-scale proteomic analyses in Escherichia coli have documented the composition and physical relationships of multiprotein complexes, but not their functional organization into biological pathways and processes. Conversely, genetic interaction (GI) screens can provide insights into the biological...

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Bibliographic Details
Main Authors: Babu, Mohan, Arnold, Roland, Bundalovic-Torma, Cedoljub, Gagarinova, Alla, Wong, Keith S., Kumar, Ashwani, Stewart, Geordie, Samanfar, Bahram, Aoki, Hiroyuki, Wagih, Omar, Vlasblom, James, Phanse, Sadhna, Lad, Krunal, Yeou Hsiung Yu, Angela, Graham, Christopher, Jin, Ke, Brown, Eric, Golshani, Ashkan, Kim, Philip, Moreno-Hagelsieb, Gabriel, Greenblatt, Jack, Houry, Walid A., Parkinson, John, Emili, Andrew
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930520/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930520/

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