Natural Polymorphisms in Tap2 Influence Negative Selection and CD4∶CD8 Lineage Commitment in the Rat

Natural Polymorphisms in Tap2 Influence Negative Selection and CD4∶CD8 Lineage Commitment in the Rat

Genetic variation in the major histocompatibility complex (MHC) affects CD4∶CD8 lineage commitment and MHC expression. However, the contribution of specific genes in this gene-dense region has not yet been resolved. Nor has it been established whether the same genes regulate MHC expression and T cel...

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Bibliographic Details
Main Authors: Tuncel, Jonatan, Haag, Sabrina, Yau, Anthony C. Y., Norin, Ulrika, Baud, Amelie, Lönnblom, Erik, Maratou, Klio, Ytterberg, A. Jimmy, Ekman, Diana, Thordardottir, Soley, Johannesson, Martina, Gillett, Alan, Stridh, Pernilla, Jagodic, Maja, Olsson, Tomas, Fernández-Teruel, Alberto, Zubarev, Roman A., Mott, Richard, Aitman, Timothy J., Flint, Jonathan, Holmdahl, Rikard
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930506/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930506/

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