Respiratory Syncytial Virus (RSV) Infection in Elderly Mice Results in Altered Antiviral Gene Expression and Enhanced Pathology

Respiratory Syncytial Virus (RSV) Infection in Elderly Mice Results in Altered Antiviral Gene Expression and Enhanced Pathology

Elderly persons are more susceptible to RSV-induced pneumonia than young people, but the molecular mechanism underlying this susceptibility is not well understood. In this study, we used an aged mouse model of RSV-induced pneumonia to examine how aging alters the lung pathology, modulates antiviral...

Full description

Bibliographic Details
Main Authors: Wong, Terianne M., Boyapalle, Sandhya, Sampayo, Viviana, Nguyen, Huy D., Bedi, Raminder, Kamath, Siddharth G., Moore, Martin L., Mohapatra, Subhra, Mohapatra, Shyam S.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928298/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928298/

Similar Items