The Evolution of Protein Structures and Structural Ensembles Under Functional Constraint

Protein sequence, structure, and function are inherently linked through evolution and population genetics. Our knowledge of protein structure comes from solved structures in the Protein Data Bank (PDB), our knowledge of sequence through sequences found in the NCBI sequence databases (http://www.ncbi...

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Bibliographic Details
Main Authors: Siltberg-Liberles, Jessica, Grahnen, Johan A., Liberles, David A.
Format: Online
Language:English
Published: MDPI 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927589/