A2A blockade enhances anti-metastatic immune responses

The specific targeting of tumor-elicited immunosuppression is a promising strategy for the treatment of cancer. We have recently demonstrated that targeting the immunosuppressive pathway mediated by CD73-derived adenosine through the blockade of A2A/A2B adenosine receptors significantly reduced the...

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Bibliographic Details
Main Authors: Beavis, Paul A, Milenkovski, Nicole, Stagg, John, Smyth, Mark J, Darcy, Phillip K
Format: Online
Language:English
Published: Landes Bioscience 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926871/