CtIP is required for DNA damage-dependent induction of P21
DNA endonuclease CtIP is involved in both DNA double-strand break (DSB) repair and transcriptional repression/activation. The cyclin-dependent kinase inhibitor P21, which is induced at transcription level in response to a variety of stresses, controls G1/S transition. In this report, we found that C...
Main Authors: | , , , , , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Landes Bioscience
2014
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925741/ |