CtIP is required for DNA damage-dependent induction of P21

DNA endonuclease CtIP is involved in both DNA double-strand break (DSB) repair and transcriptional repression/activation. The cyclin-dependent kinase inhibitor P21, which is induced at transcription level in response to a variety of stresses, controls G1/S transition. In this report, we found that C...

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Bibliographic Details
Main Authors: Liu, Bo, Cong, Rixin, Peng, Bin, Zhu, Bingtao, Dou, Gelin, Ai, Haiyan, Zhang, Xiaodong, Wang, Zhenghe, Xu, Xingzhi
Format: Online
Language:English
Published: Landes Bioscience 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925741/