Autophagy Pathway Is Required for IL-6 Induced Neuroendocrine Differentiation and Chemoresistance of Prostate Cancer LNCaP Cells

Prostate cancer (PCa) cells undergoing neuroendocrine differentiation (NED) are clinically relevant to the development of relapsed castration-resistant PCa. Increasing evidences show that autophagy involves in the development of neuroendocrine (NE) tumors, including PCa. To clarify the effect of aut...

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Bibliographic Details
Main Authors: Chang, Pei-Ching, Wang, Tao-Yeuan, Chang, Yi-Ting, Chu, Cheng-Ying, Lee, Chin-Ling, Hsu, Hung-Wei, Zhou, Tyng-An, Wu, Zhaoju, Kim, Randie H., Desai, Sonal J., Liu, Shangqin, Kung, Hsing-Jien
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925144/