Antisense Gene Silencing: Therapy for Neurodegenerative Disorders?

Since the first reports that double-stranded RNAs can efficiently silence gene expression in C. elegans, the technology of RNA interference (RNAi) has been intensively exploited as an experimental tool to study gene function. With the subsequent discovery that RNAi could also be applied to mammalian...

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Bibliographic Details
Main Authors: Nielsen, Troels T., Nielsen, Jørgen E.
Format: Online
Language:English
Published: MDPI 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924827/