WNT7B mediates autocrine Wnt/β-catenin signaling and anchorage-independent growth in pancreatic adenocarcinoma

WNT7B mediates autocrine Wnt/β-catenin signaling and anchorage-independent growth in pancreatic adenocarcinoma

Developmental and cancer models show Wnt/β-catenin-dependent signaling mediates diverse phenotypic outcomes in the pancreas that are dictated by context, duration and strength of activation. While generally assumed to be pro-tumorigenic, it is unclear to what extent dysregulation of Wnt/β-catenin si...

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Bibliographic Details
Main Authors: Arensman, Michael D., Kovochich, Anne N., Kulikauskas, Rima M., Lay, Anna R., Yang, Pei-Tzu, Li, Xinmin, Donahue, Timothy, Major, Michael B., Moon, Randall T., Chien, Andy J., Dawson, David W.
Format: Online
Language:English
Published: 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923845/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923845/

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